Therapeutic Efficacy of Molecular Hydrogen: A New Mechanistic Insight

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular hydrogen in sports medicine: new therapeutic perspectives.

In the past 2 decades, molecular hydrogen emerged as a novel therapeutic agent, with antioxidant, anti-inflammatory and anti-apoptotic effects demonstrated in plethora of animal disease models and human studies. Beneficial effects of molecular hydrogen in clinical environment are observed especially in oxidative stress-mediated diseases, such as diabetes mellitus, brain stem infarction, rheumat...

متن کامل

Molecular hydrogen: a therapeutic antioxidant and beyond

Molecular hydrogen (H2) medicine research has flourished since a landmark publication in Nature Medicine that revealed the antioxidant and cytoprotective effects of hydrogen gas in a focal stroke model. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is beyond pure hyd...

متن کامل

Models and Mechanistic Insight

" The mission of the Journal of General Physiology is to publish original work of the highest quality that elucidates basic biological, chemical, or physical mechanisms of broad physiological signifi cance. This expectation — that the articles provide mechanistic insight — has served the Journal well; it also has been cause for much uncertainty , mostly pertaining to what actually constitutes m...

متن کامل

New insights into the molecular basis of atrial fibrillation: mechanistic and therapeutic implications.

Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial cardiovascular morbidity and mortality, with stroke being the most critical complication. Present drugs used for AF therapy have major limitations, including incomplete efficacy and risks of life-threatening proarrhythmic events and bleeding complications. Non-pharmacological ablation procedures are e...

متن کامل

Nutraceuticals against Neurodegeneration: A Mechanistic Insight

The mechanisms underlying neurodegenerative disorders are complex and multifactorial; however, accumulating evidences suggest few common shared pathways. These common pathways include mitochondrial dysfunction, intracellular Ca2+ overload, oxidative stress and inflammation. Often multiple pathways co-exist, and therefore limit the benefits of therapeutic interventions. Nutraceuticals have recen...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Pharmaceutical Design

سال: 2019

ISSN: 1381-6128

DOI: 10.2174/1381612825666190506123038